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KMID : 0614620090530060355
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Korean Journal of Gastroenterology
2009 Volume.53 No. 6 p.355 ~ p.360
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A Study on Viral Hepatitis Markers and Abnormal Liver Function Test in Adults Living in Northwest Area of Chungnam
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Kim Suk-Bae
Lee Won-Kyung
Choi Hoon
Kim So-Mi
No Ran
Kang Ha-Yan
Lee Sang-Seok
La Sung-Soo
Kong Jae-Hwan
Shin Hyun-Deok
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Abstract
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Background/Aims: We studied the prevalence of chronic hepatitis B, C and abnormality on liver function among the population in northwest area of Chungnam.
Methods: We have reviewed 40,112 adults who had received medical examination at health promotion center in Dankook university hospital. We studied them retrospectively about HBsAg, HBsAb, anti-HCV, and liver function test (LFT).
Results: Among the study subjects, 22,936 men and 17,176 women were involved. The overall seroprevalence of HBsAg was 4.2%. The prevalence in men (4.5%) was higher than that of women (3.7%) (p＜0.001). The seroprevalence of HBsAg in their age was 5.1% in the 5th decade, 4.2% in the 2nd decade, 4.1% in the 4th decade, and 4.1% in the 6th decade. The overall seroprevalence of HBsAb was 65.1%. The overall seroprevalence of anti-HCV was 0.7%. After we reexamined them with HCV RNA or RIBA (Recombinant Immunoblot Assay), the prevalence of chronic hepatitis C was 0.09%. The LFT abnormality in total subjects was 11.4%. The LFT abnormality of chronic hepatitis B and C subjects was 21.72% and 63.2%.
Conclusions: The prevalence of chronic hepatitis B and C was lower than that of previous studies. The prevalence of chronic hepatitis B in the 2nd decade was still high.
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KEYWORD
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Prevalence, HBsAg, Anti-HCV, Abnormal LFT
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